To establish and evaluate a new prediction model for assessing cardiovascular disease risk in community-dwelling adults.
This is an ambispective, observational cohort study. In the retrospective part, we will enroll residents from Guangzhou or Foshan who participated in the annual health checks provided by the Chinese National Basic Public Health Service project between January 2015 and December 2019. The demographic characteristics, anthropometric measurements, laboratory assays, medical history, living habits, and medications will be collected through personal electronic health records obtained from the regional chronic disease management platform. In the prospective part, residents who participated in the annual health checks provided by the Chinese National Basic Public Health Service project after January 2020 will be enrolled. In addition to the data collected in the retrospective part, blood, urine and fecal samples and lifestyle questionnaires will be collected for further analysis. All participants will be followed-up till December 2025. A new prediction model for assessing cardiovascular disease risk will be established and evaluated.
Study Type
OBSERVATIONAL
Enrollment
20,000
The Fourth People's Hospital of Foshan
Foshan, Guangdong, China
RECRUITINGNanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China
RECRUITINGMajor adverse cardiovascular events
Major adverse cardiovascular events include all-cause mortality, acute myocardial infarction, coronary heart disease, heart failure and stroke.
Time frame: 5 years
Atherosclerotic cardiovascular events
Atherosclerotic cardiovascular events include acute myocardial infarction, coronary heart disease, heart failure and fatal and non-fatal stroke.
Time frame: 5 years
All-cause mortality
Defined as any death after enrollment.
Time frame: 5 years
Cognitive dysfunction
Defined as Montreal Cognitive Assessment (MoCA) Score \< 26 points.
Time frame: 5 years
Renal functional deterioration
Evaluated through change in estimated glomerular filtration rate.
Time frame: 5 years
Renal replacement therapy and/or death due to acute renal failure
Time frame: 5 years
Incident atrial fibrillation
Atrial fibrillation is diagnosed according to the 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation.
Time frame: 5 years
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.