The purpose of the study is to understand the effect of dietary fiber on patients with polycystic ovary syndrome.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
100
dietary fiber (Inulin 4g,Resistant Starch 4g,β-glucan 2g)
Peking University Third Hospital
Beijing, Beijing Municipality, China
RECRUITINGChanges in gut microbiota
Study the gut microbiota change of stool samples between placebo group and intervention group
Time frame: before and after 2,4,8,12 weeks of intervention
Changes in metabolomics
Study the netabolomics change of stool samples between placebo group and intervention group
Time frame: before and after 2,4,8,12 weeks of intervention
Changes in endocrine hormones
Study the hormones change of blood samples between placebo group and intervention group
Time frame: before and after 12 weeks of intervention
Changes in ovarian volume
The size of each ovary will be determined using transvaginal ultrasonography for each participant in early follicular phase.
Time frame: before and after 12 weeks of intervention
Changes in the number of follicles
The number of follicles of each ovary will be determined using transvaginal ultrasonography for each participant in early follicular phase.
Time frame: before and after 12 weeks of intervention
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