This is a prospective, open large cohort study to explore biomarkers for detecting early carcinogenesis of IPMN.
This prospective study was designed to explore biomarkers for detecting early carcinogenesis of IPMN. This study intends to prospectively and continuously enroll IPMN patients, and regularly collect biological samples including blood, urine, feces and saliva. We aimed to detect biomarkers which can predict the carcinogenesis of IPMN by multi-omics. The primary endpoint is the predictive accuracy of biomarkers for IPMN malignant transformation. The probability of IPMN malignant transformation , rates of surgical resection and survival after surgery are secondary endpoints.
Study Type
OBSERVATIONAL
Enrollment
5,000
This is an observational study.
the First Affiliated Hospital, School of Medicine, Zhejiang University
Hangzhou, Zhejiang, China
RECRUITINGThe accuracy of IPMN malignant transformation
Time frame: Up to 10 years
the probability of IPMN malignant transformation
Time frame: Up to 10 years
rates of surgical resection
Time frame: Up to 10 years
survival after surgery
Time frame: Up to 10-15 years
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