This study will be an open-label superiority, multicenter, single-blind, controlled randomized clinical trial investing the role of a PVP-I irrigation solution (Surgiphor) in reducing the risk of acute PJI in the 90 days following total hip and knee revision arthroplasty.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
868
use of Surgiphor wound irrigation solution during surgery
Use of sterile saline as a irrigation solution during surgery
University of Arizona
Phoenix, Arizona, United States
Lifebridge Health
Baltimore, Maryland, United States
University of Missouri
Columbia, Missouri, United States
Rothman Institute Orthopaedics
Philadelphia, Pennsylvania, United States
Diagnosis of acute prosthetic joint infection
Diagnosis of acute prothetic joint infection following aseptic revision surgery
Time frame: Within 90 days of revision surgery
Wound complications
Diagnosis of wound complication, surgical site infections or other infections within 1 year of surgery
Time frame: within 1 year of revision surgery
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