National Multicenter Cohort Registry Study of Rapid rEcurrences of Coronary Unexplained In-stent Restenosis

China National Center for Cardiovascular Diseases1,000 enrolled

Overview

This project aims to establish a clinical cohort and diagnostic assessment framework by conducting a national multicenter cohort registry study. Through the collection of patients' clinical characteristics, it will achieve the registration, management, follow-up, and analysis of patients with Rapid rEcurrences of Coronary Unexplained in-stent Restenosis (RECUR).

Study Type

OBSERVATIONAL

Enrollment

1,000

Conditions

Coronary Artery Disease Arteritis In-Stent Stenosis (Restenosis) of Coronary Artery Stent

Interventions

Treatment made by experienced cliniciansOTHER

Treatment made by experienced clinicians

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Age ≥ 18 years; 2. Patients meeting the diagnostic criteria for Rapid rEcurrences of Coronary Unexplained in-stent Restenosis (RECUR); 3. Patients fully informed about the trial procedures who provide written informed consent. Exclusion Criteria: 1. Patients presenting with any of the following: * Other severe comorbidities (e.g., malignant tumors, heart failure) with a life expectancy \<12 months; * Known autoimmune/rheumatic diseases including systemic lupus erythematosus, Takayasu arteritis, Behçet's disease, polyarteritis nodosa, Wegener granulomatosis (granulomatosis with polyangiitis), eosinophilic arteritis, giant cell arteritis, rheumatoid arthritis, or IgG4-related disease; * Variant angina (Prinzmetal's angina); * Coronary artery dissection; * Thrombophilia; * Stent underexpansion. 2. Presence of psychiatric disorders; 3. Known inability to complete expected study follow-up for any reason; 4. Patients deemed ineligible for enrollment by the investigator.

Outcomes

Primary Outcomes

Target vessel failure

Time to the incidence of target vessel failure, a composite of cardiovascular death, target vessel-related myocardial infarction, and target vessel-related revascularization.

Time frame: 10 year