Unicompartmental Knee Arthroplasty vs. High Tibial Osteotomy for Medial Knee Osteoarthritis (UNIKORN): a Study Protocol of a Randomized Controlled Trial

Töölö Hospital100 enrolled

Overview

Unicompartmental knee arthroplasty (UKA) and High Tibial Osteotomy are both valid treatment options for isolated medial knee osteoarthritis. Literature to date is lacking high grade evidence of the outcomes between these procedures. This is a study protocol for randomized controlled trial comparing UKA vs HTO in late stage medial knee osteoarthritis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

100

Conditions

Knee Osteoarthritis

Interventions

Unicompartmental knee arthroplastyPROCEDURE

Medial Unicompartmental knee arthroplasty

High tibial osteotomyPROCEDURE

Medial open wedge high tibial osteotomy

Eligibility

Sex: ALLMin age: 45 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Isolated KL 3-4 medial knee arthrosis * Varus \> 3 degrees * Age 45-65 years Exclusion Criteria: * Post-traumatic arthrosis * Arthrosis in the lateral compartment more than KL grade I in MRI * Post- traumatic arthrosis * Instability * Malignancy Obesity

Outcomes

Primary Outcomes

KOOS

Time frame: 1- year

Central Contacts

Juuso Siren, MD

CONTACT

0407005858 juuso.siren@hus.fi

Data from ClinicalTrials.gov

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