Following increased knowledge about climate change and how food production affects greenhouse gas emissions, the interest in vegetarian diets is increasing. In line with this, also vegan diet is becoming more common at all ages, including in young children. But the state of knowledge regarding the effect of this diet on children during infancy and early childhood has been poorly studied and existing literature consists to a large extent of case reports. With the main hypothesis that vegan diet from the introduction of complementary foods causes reduced bio availability of certain micronutrients important for development, the aim of this study is to examine dietary intake and development during the first years of life in a group of children eating vegan diet and compare with a reference group eating mixed diets. In an observational study, investigators plan to include 30 children before the age of 6 months during the years 2021-2026, where the parents have decided to offer their child only vegan food. The children are studied in comparison with a reference group of 30 matched cases regarding growth, nutritional status, and dietary intake. Data collection includes monthly dietary records and blood sample analyses and growth at 6, 12 and 24 months. At the age of 3, cognitive developmental assessment (WPSSI-IV) and an DEXA examination of body composition are performed. The study is expected to contribute to increased knowledge about the risk and benefits of vegan diets and thereby provide a better basis for future recommendations.
Study Type
OBSERVATIONAL
Enrollment
60
Umeå University, Department of Clinical Sciences
Umeå, Umeå, Sweden
Concentration of Hemoglobin
Blood
Time frame: 12 months of age
Body Weight (kg)
measured weight at 12 mo using a device for measuring weight
Time frame: 12 months of age
Wechsler Preschool & Primary Scale of Intelligence
Scale for cognitive development. Expected mean 100. Higher scores equals better cognitive development.
Time frame: 3 years of age
Fat mass index
FMI, measured by DEXA-scan
Time frame: 3 years of age
Lean mass index
LMI, measured by DEXA-scan
Time frame: 3 years of age
Protein intake
3 day food diary
Time frame: at 12 months of age
Fat intake
3 day food diary
Time frame: at 12 months of age
Carbohydrate intake
3 day food diary
Time frame: at 12 months of age
Iron intake (mg/day)
3 day food diary
Time frame: throughout study
B12 levels
Serum sample
Time frame: 6, 12, 24, 36 months
Zink level
Serum sample
Time frame: 6, 12, 24, 36 months
D-vitamin levels
Serum sample
Time frame: 6, 12, 24, 36 months
Calcium levels
Serum sample
Time frame: 6, 12, 24, 36 months
Homocysteine levels
serum sample
Time frame: 6, 12, 24, 36 months
Transferrin receptor concentration
Serum sample
Time frame: 12 months of age
Transferrin saturation
serum sample
Time frame: 12 months of age
Mean cell volume
Blood sample
Time frame: 12 months of age
Ferritin
Serum sample
Time frame: 12 months of age
Length of body
measured length at 12 mo using measuring tool for children
Time frame: 12 months of age
Circumference of the head
measured at 12 mo using measuring tool for children
Time frame: 12 months of age
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.