AFHRI is planned as a prospective, single-center cohort study in patients at high risk of AF.
The primary aim of the study is to evaluate and improve atrial fibrillation risk prediction, which takes into account clinical, psycho-social, environmental and lifestyle-risk factors, protein patterns and genetic variability in addition to the classical risk factors with respect to the primary endpoint, AF (paroxysmal or permanent).
Study Type
OBSERVATIONAL
Enrollment
3,000
Department of Cardiology, University Medical Center Hamburg-Eppendorf
Hamburg, Germany
RECRUITINGIncident atrial fibrillation
12-lead Electrocardiogram (ECG) tracing, diagnosis of AF will be made if at least two cardiologists verify the rhythm abnormality using clinic visit, outside physician or hospital records, or ambulatory ECG reports.
Time frame: up to 4 years
Myocardial infarction
Typical rise and gradual fall (Troponin) or more rapid rise and fall (CK-MB) of biochemical markers of myocardial necrosis
Time frame: up to 4 years
Cardiovascular death
if no other underlying cause of death is diagnosed: hypertension, coronary heart disease, other cardiovascular disease, atherosclerosis, diabetes mellitus, dyslipidemia, obesity, sudden death and cardiac symptoms
Time frame: up to 4 years
Heart failure
echocardiography including Doppler-flow measurement
Time frame: up to 4 years
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