Disease recurrence and metastasis are common after curative treatment for patients with esophageal cancer. Thus, it is important to identify the risk factors to predict disease recurrence and metastasis. Pleural lavage cytology (PLC) is reported to be associated with disease recurrence and patient survival in lung cancer, but the value is unclear in esophageal cancer. The aim of this study is to evaluate the value of PLC in esophageal cancer patient in terms of frequencies, association with patient survival, and efficacy of postoperative treatment.
Pleural lavage cytology will be performed before esophageal resection, and after resection, respectively. Frequency of positive pleural lavage cytology will be determined, and the value of pleural lavage cytology for patients with resectable esophageal cancer will be studied.
Study Type
OBSERVATIONAL
Enrollment
385
pleural lavages before tumor resection and after tumor resecion, respectively
The First Affiliated Hospital of USTC
Hefei, Anhui, China
NOT_YET_RECRUITINGThe Fourth Hospital of Hebei Medical University
Shijiazhuang, Hebei, China
NOT_YET_RECRUITINGHenan Provincial People's Hospital
Zhengzhou, Henan, China
NOT_YET_RECRUITINGNantong Tumor Hospital
Nantong, Jiangsu, China
NOT_YET_RECRUITINGThe Second Affiliated Hospital of Nantong University
Nantong, Jiangsu, China
NOT_YET_RECRUITINGTaixing People's Hospital
Taishing, Jiangsu, China
RECRUITINGTaizhou People's Hospital
Taizhou, Jiangsu, China
NOT_YET_RECRUITINGShaanxi Provincial cancer Hospital
Xi'an, Shaanxi, China
NOT_YET_RECRUITINGThe First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shannxi, China
NOT_YET_RECRUITINGTianjin Medical University Cancer Institute
Tianjin, Tianjin Municipality, China
NOT_YET_RECRUITING...and 1 more locations
number of patients who had positive pleural lavage cytology
Frequency of positive pleural lavage cytology in resectable esophageal squamous cell carcinoma
Time frame: July 2022 to July 2023
Time period from date of surgery to the date of death
value of pleural lavage cytology in predict patient survival
Time frame: July 2022 to July 2026
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