The Effect of Low Dose Ketamine on Narcotic Consumption in Patients Undergoing Laparoscopic Cholecystectomy

Aga Khan University86 enrolled

Overview

This double-blinded randomized control trial aims to analyze the effect of low dose Ketamine on narcotic consumption, in patients undergoing Laparoscopic cholecystectomy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Cholelithiasis

Interventions

Ketamine HydrochlorideDRUG

Ketamine was given prior to wound closure.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * all ASA 1 and 2 patients undergoing Laparoscopic Cholecystectomy electively. Exclusion Criteria: * Hepatic and renal disease and ASA 3 and 4 patients.

Outcomes

Primary Outcomes

pain score using Visual Analogue scale, ranging from 0 (minimum) and 10 (maximum), 3 and below showing no pain and scores above 3 showing moderate to severe pain.

Change in pain score using Visual Analogue Scale

Time frame: Baseline on arrival in the post anaesthesia care unit and then every fifteen minutes unto one hour

Secondary Outcomes

narcotic consumption in the post operative anaesthesia care unit

requirement of narcotic in the post anaesthesia care unit

Time frame: postoperatively, after arrival in the post anaesthesia care unit at every fifteen minutes unto one hour

Data from ClinicalTrials.gov

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