This is a prospective, single arm study to investigate the efficacy and safety furmonertinib 80mg/d as adjuvant treatment for 3 years post surgery of stage IA with high-risk factors and stage IB non-small cell lung cancer. A total of 114 patients would be enrolled. The primary endpoint is the disease-free survival rate at 3 years.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
114
Furmonertinib 80mg/d
Peking Union Medical College Hopital
Beijing, China
RECRUITINGDisease-free survival rate at 3 years
The rate of survival patients without disease recurrence at 3 years
Time frame: 3 years following the first dose of study drug
Overall survival rate at 3 years
The rate of survival patients at 3 years
Time frame: 3 years following the first dose of study drug
Median disease-free survival
The median time from the enrollment to the disease recurrence or death depending on the protocol
Time frame: Approximately 3 years following the first dose of study drugs
Median overall survival
The median time from the enrollment to death of any cause depending on the protocol
Time frame: Approximately 5 years following the first dose of study drugs
Adverse events
The number of patients with adverse events and the severity according to CTCAE v5.0
Time frame: Approximately 3 years following the first dose of study drugs
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