Serum YKL-40 Level and Platelets Indices Among Patients With Diabetic Erectile Dysfunction

Aswan University60 enrolled

Overview

The aim of this current study is to estimate serum level of YKL-40, serum total testosterone and platelets indices in diabetic patients with erectile dysfunction treated by daily tadalafil 5mg for 3 months.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Erectile Dysfunction Erectile Dysfunction With Diabetes Mellitus

Interventions

Tadalafil 5mgDRUG

* Estimate serum level of serum YKL-40, total testosterone and platelets indices in diabetic patients with erectile dysfunction treated by daily tadalafil 5mg for 3months. * Penile color Doppler ultrasound examination before and after treatment

Eligibility

Sex: MALEMin age: 30 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Diabetic patients with ED. Exclusion Criteria: * Patients with history of pelvic trauma. * Patients with major pelvic surgical intervention. * Patients with hypogonadism and hyperprolactinemia. * Patients with chronic liver disease. * Patients with cardio vascular system diseases. * History of chronic intake of central nervous system, anti androgen drugs or other drugs as Tramadol. * Smokers patients. * Patients with non-vasculogenic Erectile dysfunction.

Locations (1)

Aswan university

Aswān, Egypt

Outcomes

Primary Outcomes

Serum YKL-40 and platelets indices in erectile dysfunction

Measurement of YKL-40 and platelets indices in diabetic patients with erectile dysfunction treated by daily tadalafil.

Time frame: 3 months

Secondary Outcomes

Effect of tadalafil on Erectile dysfucntion patients

To show the therapeutic effect of tadalafil in dose 5 mg daily on Erectile dysfucntion patients and assess their response by international index of erectile function (IIEF-5)

Time frame: 3 months

Data from ClinicalTrials.gov

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