Coexistence HBsAg/HBcAC, Clinical Characterístics & Outcomes

Corporacion Parc Tauli120 enrolled

Overview

HBV infection is a dynamic process with complex interactions between virus replication and the host's immune response. The appearance of anti-HBs after HBV infection generally indicates recovery and immunity to HBV1 infection. However, there are several published studies that describe the coexistence of the marker of chronic infection (HBsAg +) and the marker of functional cure (HBsAc +). There are contradictory studies on whether the coexistence of HBsAg/HBsAc implies a different clinical course.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Hepatitis B

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * all those patients who have been seen in outpatient hepatology consultations and who present positive HBsAg and HBsAc serology simultaneously. Exclusion Criteria: * Hepatitis C or HIV Co-infection

Locations (1)

H. Consorci Sanitari Parc Tauli

Sabadell, Barcelona, Spain

Outcomes

Primary Outcomes

prevalence concomitant HBsAg and HBsAc markers

To describe the prevalence of concomitant HBsAg and HBsAc markers in our area

Time frame: 10 years

Secondary Outcomes

differences between immunocompetent patients with respect to immunocompromised ones.

To compare if there are differences in the prevalence or clinical outcome according if the patient has any degree of immunosupresion or not.

Time frame: 10 years

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.