Corneal Endothelium After Phacoemulsification in Pseudo Exfoliation Syndrome

Minia University40 enrolled

Overview

To study corneal endothelial cells changes after phacoemulsification in patients with senile cataract and pseudoexfoliation syndrome (PEX) compared with control patients with senile cataract using specular microscope.

In a prospective interventional case-control study, 20 eyes with cataract and PEX and 20 control eyes with cataract without PXE were subjected to phacoemulsification and posterior chamber foldable intraocular lens implantation in Minia University Hospital and Genaidy Eye Center between March 2019 and December 2020. Specular microscopy was done preoperatively, 3 and 6 months postoperatively. Endothelium cell density (ECD), coefficient variation (CV), hexagonality, pleomorphism and corneal thickness were evaluated and compares between PXE and control eyes.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Corneal Endothelial Cell Loss Pseudoexfoliation Syndrome

Interventions

phacoemulsificationPROCEDURE

phacoemulsification with corneal endothelial evaluation by specular microscopy

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * senile cataract age more than 55 years Exclusion Criteria: * PEX with glaucoma, eyes with cornea guttata or any corneal dystrophy, zonular dehiscence, very dense nuclear cataract (cataracta nigra) history of previous ocular surgery.

Locations (1)

Minia University Hospital

Minya, Minya Governorate, Egypt

Outcomes

Primary Outcomes

corneal endothelial cell loss

Time frame: 6 months

Data from ClinicalTrials.gov

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