Evaluation of the Effect of Chicory Inulin-type Fructans in Constipated Adults

Sensus40 enrolled

Overview

Constipation is common in the general population, especially in women and in the elderly, which can significantly affect quality of life of the individual. There is a general consumer trend to seek natural food options, also when addressing health issues such as constipation. Consumers seek tasty options and there is a paucity of tasty functional foods to address constipation. Adding natural fiber to food, like inulin-type fructans from chicory root fiber, can increase fiber intake and potentially prevent or resolve constipation issues. This study aimed to increase the body of scientific data on inulin-type fructans by way of a randomized, placebo-controlled, cross-over study. Maltodextrin was used as the placebo in this study.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Constipation - Functional

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Able to give written informed consent * Between 18 and 75 years of age * Have functional constipation according to the Rome III Diagnostic Criteria * Subjects were to continue on their normal diet and agreed to not take probiotic or prebiotic products/supplements and supplemental dietary fibres for the duration of the study * The subject agrees to complete the Patient Diary for two weeks prior to study entry and for the duration of the study * Subject is in general good health as determined by the investigator. Exclusion Criteria: * Subjects less than 18 and greater than 75 years of age * Females who are pregnant, lactating or wish to become pregnant during the study. * Subjects who are hypersensitive to any of the components of the test product, * Subjects who have an obstructive or metabolic aetiology for constipation, * Subjects who have a history of laxative abuse (greater than the daily dosage recommended on the label for any laxative), * Subjects currently taking supplemental dietary fibres or have taken them within two weeks of the screening visit, * Subjects who are taking a probiotic or prebiotic product/supplement or had taken them within two weeks of the screening visit