The study will investigate the effect of smart monitoring on medication adherence.
In this study, multiple medication monitoring procedures will be performed: self-reporting, pill counting, smart monitoring and concentration monitoring. Subjects will take vitamin D supplement on the market which enables validated concentration monitoring. The study will last for 3 months.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
16
Self monitoring using smart clinical trial application
Smart watch-assisted adherence monitoring
Vitamin D self-administration for 3 months
Seoul National University Hospital Clinical Trial Center
Seoul, South Korea
The percentage of prescribed doses taken
Percentage of doses taken
Time frame: 3 months
The percentage of days with correct dosing
Taking adherence
Time frame: 3 months
The percentage of days with correct dosing window
Timing adherence
Time frame: 3 months
Days without medication intake during a time period longer than 24 h
Drug holiday
Time frame: 3 months
Mean difference between administration time point and the mode of administration time point
Timing distribution index
Time frame: 3 months
Sum of deviations divided by the number of days
Concurrence of medication adherence records
Time frame: 3 months
Serum concentration of vitamin D
Vitamin D concentration
Time frame: 3 months (Day 1, 15, 29, 43, 57, 71, 85)
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