Nutricia has a range of nutritionally complete tube feeds on the market including some specific for diabetes patients. A new product is currently under development. The aim of the present study is to assess whether the postprandial glucose response of the new product is equivalent to the postprandial glucose response of an original product. In addition, the Glycaemic Index (GI) and Glycaemic Load (GL) of the adapted product will be determined. The study will have a crossover design with healthy volunteers taking one serving of both products in a randomized order. To determine GI and GL of the adapted product subjects will also receive a reference product. Subjects will visit the study site six times: one screening visit, three study visits to measure the glucose response to the reference product and two study visits to measure the glucose response to the test and control product.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
22
1\) Intervention type: Dietary Supplement Intervention name: (visits 1, 3 and 5) Reference product Intervention description: Glucose solution 2) Intervention type: Dietary Supplement Intervention name: (visit 2 or 4) Diabetes specific tube feed Intervention description: : One serving new product 3) Intervention type: : Dietary Supplement Intervention name: (visit 2 or 4) Diabetes specific tube feed Intervention description: One serving original product
NCRU
Utrecht, Netherlands
Blood glucose - Product A versus Product B
Blood glucose iAUC0-120 \[mmol/L\*min\] \[mmol/L\]
Time frame: 120 minutes
Blood glucose - Product A versus Product B
Blood glucose iCmax \[mmol/L\] \[mmol/L\]
Time frame: 120 minutes
GI new product
GI = blood glucose iAUC0-120 \[mmol/L\] of new product / mean blood glucose iAUC0-120 \[mmol/L\] of reference product
Time frame: 120 minutes
GL new product
GL = GI \* available carbohydrate/given amount of carbohydrate
Time frame: 120 minutes
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