This is a open-label, phase 2 study to evaluate the efficacy, safety and PK of CD7 chimeric antigen receptors treatment for patients with refractory/relapsed CD7 positive hematological malignancies.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
14
Universal CAR-T cells targeting CD7
Institute of Hematology & Blood Diseases Hospital
Tianjin, China
Overall Response Rate(ORR)
Number of patients who achieved response after treatment of CD7 CAR-T cell.
Time frame: 1 Year
Duration of overall response (DOR)
Duration of overall response will be assessed from the CAR-T cell infusion to progression, death or last follow-up.
Time frame: 1 Year
Overall survival(OS)
OS will be assessed from the CAR-T cell infusion to death or last follow-up.
Time frame: 1 Year
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