The aim of the study to investigate the relationship between femoral cartilage thickness in Ultrasonographic evaluation and inflammatory parameters, pain severity and functionality in participants with Knee Osteoarthritis
Aim: The aim of the study is to investigate the relationship between femoral cartilage thickness and inflammatory parameters, pain severity and functionality in participants with Knee Osteoarthritis. Methods: This study is designed as a prospective, cross-sectional trial. 90 participants aged between 50-65 years with knee osteoarthritis(OA) and at least 50 participants without any symptom for knee OA are included in the study in accordance with the inclusion criteria. Participants' demographic characteristics will be evaluated, and ultrasonographic measurement will be performed for measuring femoral cartilage thickness. Visual Analog scale will be used for pain severity and Western Ontario and McMaster Universities Osteoartrit index (WOMAC) will be used for assessing functionality of the patients. Also hematologic parameters(neutrophils, leucocytes, lymphocytes, platelet, CRP, erythrocyte sedimentation rate) will be evaluated for investigating the inflammation. The relationship between femoral cartilage thickness and inflammatory parameters, pain severity and functionality in knee osteoarthritis will be analysed for both group.
Study Type
OBSERVATIONAL
Enrollment
140
ultrasonographic measurement for femoral cartilage thickness VAS for pain severity WOMAC for functionality
Kanuni Sultan Suleyman Training and Research Hospital
Istanbul, Kucukcekmece, Turkey (Türkiye)
RECRUITINGultrasonography
measurement of femoral cartilage thickness
Time frame: 1 day
Visual Analog Scale
evaluation of pain severity
Time frame: 1 day
Western Ontario and McMaster Universities Osteoarthritis Index
evaluation of functionality
Time frame: 1 day
neutrophil account
neutrophil account
Time frame: 1 day
lymphocyte account
lymphocyte account
Time frame: 1 day
monocyte account
monocyte account
Time frame: 1 day
platelet account
platelet account
Time frame: 1 day
eritrocyte sedimentation rate
eritrocyte sedimentation rate
Time frame: 1 day
C-reactive protein
C-reactive protein
Time frame: 1 day
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