The study aims to explore the potential of combination therapy with fractional radiofrequency and topical tretinoin for treatment and overall improvement of striae albae. We also aim to assess subject satisfaction, local skin responses and adverse effects/reactions in relation to the treatments, alone and in combination.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
20
Treatment of striae with fractional radiofrequency and topical tretinoin in combination
Treatment of striae with topical tretinoin alone
Treatment of striae with fractional radiofrequency alone
Department of Dermatology, Bispebjerg Hospital
Copenhagen, Denmark
Improvement in appearance of striae with GAIS
Standardized clinical photos from baseline and follow-up comparing treatments and assessed by blinded evaluator on the Global Aesthetic Improvement Scale (GAIS)
Time frame: Baseline, at 4 weeks, 8 weeks and 20 weeks follow-up
Evaluation of striae with POSAS
Standardized on-site assessment comparing treatments assessed by the subject and a blinded evaluator on the Patient-Observer Scar Assessment Scale (POSAS)
Time frame: Baseline - 20 weeks follow-up (12 weeks after last treatment)
Evaluation of striae with imaging
Assessment of tissue interaction with imaging techniques
Time frame: Baseline, at 4 weeks, 8 weeks and 20 weeks follow-up
Subject satisfaction
Likert scale for subject satisfaction
Time frame: Baseline - 20 weeks follow-up (12 weeks after last treatment)
Safety: LSR and AE/AR
Collection and registration of local skin reactions and AE/AR
Time frame: Baseline, at 4 weeks, 8 weeks and 20 weeks follow-up
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.