Cholangitis is the most common postoperative complication of biliary atresia, with a reported incidence of 40-90%, which seriously affects the surgical effect, survival rate and the quality of life and prognosis of patients. Without of direct evidence, the diagnosis of cholangitis sometimes is difficult to make, thus most of them are diagnosed based on the symptoms of children. According to literature reports, different centers and regions have different diagnostic criteria for postoperative cholangitis after hepatic portoenterostomy, which has a great influence on the accuracy of the incidence rate and appropriate treatment of cholangitis, and also brings differences in the analysis of the causes and prognostic factors of cholangitis. Based on the above reasons, we used the Delphi method,in which worldwidely 48 experts participated in, to establish the diagnostic scoring system for postoperative cholangitis after biliary atresia. Now we aimed to verify the specificity and sensitivity of the new scoring system through clinical cases, in order to unify and standardize the diagnostic criteria and provide help for the diagnosis and treatment of cholangitis after biliary atresia.
Study Type
OBSERVATIONAL
Enrollment
500
Treatment is usually performed with sensitive third-generation cephalosporins, and medication is adjusted according to blood culture results
NJMU
Nanjing, Jiangsu, China
RECRUITINGDiagnostic cholangitis score
The values of the two groups' scores were calculated separately
Time frame: Two years
Score estimates for treatment of cholangitis
In the cholangitis group, the correlation between evaluation score and treatment was studied
Time frame: Two years
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