This study will evaluate the efficacy of the a 15% trichloroacetic acid + 3% glycolic acid peel combination for treatment of lentigines on the hands. This peel combination is sold over the counter. Patients will receive 3 treatments (spaced 4 weeks).
This clinical investigation is a prospective study consisting of a screening visit, 3 treatment visits, and 1 follow-up visit. Baseline and post-treatment photos will be graded and compared. A total of 20 patients will be recruited. Following informed consent and screening, subjects' dorsal hands will be photographed. Patients will receive 3 treatments with the 15% TCA + 3% glycolic acid peel every 4-6 weeks on the dorsal hands. Post-treatment, patients will be instructed to apply Aquaphor to the treated area twice daily for 5 days. Patients' hands will be photographed at each visit. Four to six weeks after their final treatment, subjects will return for photography.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
20
Treatment of the hand with an over-the-counter chemical peel containing 15% trichloroacetic acid + 3% glycolic acid
Main Line Center for Laser Surgery
Ardmore, Pennsylvania, United States
Improvement in hand lentigines on a 5-point scale
Photos will be graded on a 5 point scale (0=no change, 1=1-25% change, 2=26-50% change, 3=51-75% change, 4=76-100% change)
Time frame: 4-6 weeks after last treatment
Improvement in hand lentigines using the Global Aesthetic Improvement Scale
The GAIS is a validated scale assessing overall change after aesthetic procedures
Time frame: 4-6 weeks after last treatment
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