Evaluation of the Anti-aging Efficacy of Four Skin Health Products

Inclusion Criteria: * Written Informed Consent to participate in the study * Willingness to actively participate in the study and to come to the scheduled visits * Female and male * From 40 to 65 years of age * BMI \< 30 kg/m2 * Healthy skin in the test areas * Uniform skin color and no erythema or dark pigmentation in the test area * Visible wrinkle in the face (grade 3 to 6 according to proderm scale) see Appendix 2 * Ethnicity: at least one Black, Asian and Hispanic subject per study group Exclusion Criteria: * Female subjects: Pregnancy or lactation * Drug addicts, alcoholics * AIDS, HIV-positive or infectious hepatitis * Conditions which exclude a participation or might influence the test reaction/evaluation * Participation or being in the waiting period after participation in cosmetic and/or pharmaceutical studies pertaining to the test area * Active skin disease at the test area * Documented allergies to face/eye care products * Diabetes mellitus * Cancer not being diagnosed as cured and requiring chemotherapy, irradiation and/or hormonal treatment within the last 2 years One of the following illnesses with reduced physical capability/fitness: asthma (symptom-free allergic asthma is not an exclusion criterion), hypertension (if not adjusted with medication), cardiovascular diseases * Epilepsy * Wounds, moles, tattoos, scars, irritated skin, excessive hair growth, freckles, etc. at the test area that could influence the investigation * Sun-tanned skin (important for the subgroup of subjects planned for Raman measurements) * Regular use of tanning beds * Any topical medication at the test area within the last 7 days prior to the start of the study * Systemic therapy with immuno-suppressive drugs (e.g. corticosteroids) and/or antihistamines (e.g. antiallergics) and/or within the last 7 days prior to the start of the study * Past cosmetic surgery procedure in the test area (e.g. laser, facelift) * Cosmetic surgery procedure in the test area, e.g. IPL (Intensed Pulsed Light), botox, chemical peel, dermabrasion within the last 2 years prior to the start of the study and/or throughout the entire course of the study * Medical treatment for wrinkle reduction (e.g. peeling with vitamin A or fruit acids) on the face within the last 2 weeks prior to the start of the study