A research team member will brush the inferior surface of the subjects' middle turbinate (nasal cavity) using a cytology brush to obtain the cells needed to perform our functional respiratory assays. An individual trained in phlebotomy will draw one 3 ml lavender top tube of blood to test c-reactive protein, calprotectin, and lactoferrin. They will also draw a 5 ml gold top serum separator tube of blood to test fibroblast growth factor-19. The participant will answer questions from the baseline survey and report their current medications interview-style with the research team member.
Study Type
OBSERVATIONAL
Enrollment
160
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States
Comparison of Chloride Transport Values
Comparison of chloride transport values in cystic fibrosis carrier group vs control group via t-test.
Time frame: At baseline
Comparison of Bicarbonate Transport Values
Comparison of bicarbonate transport values in cystic fibrosis carrier group vs control group via t-test.
Time frame: At baseline
Comparison of Airway Surface Liquid pH Values
Comparison of airway surface liquid pH values in cystic fibrosis carrier group vs control group via t-test.
Time frame: At baseline
Comparison of Mucous Viscosity Values
Comparison of mucous viscosity values in cystic fibrosis carrier group vs control group via t-test.
Time frame: At baseline
Comparison of Bacterial Killing Values
Comparison of bacterial killing values in cystic fibrosis carrier group vs control group via t-test.
Time frame: At baseline
Comparison of Fibroblast Growth Factor-19 Values
Comparison of fibroblast growth factor-19 values in cystic fibrosis carrier group vs control group via t-test.
Time frame: At baseline
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