The study targets postoperative delirium in patients undergoing major abdominal surgery, with the aim to evaluate the functional baseline and proteomics implicated in pathogenesis, prevention strategies (such as anesthesia depth monitoring) and incidence in certain population groups.
Study Type
OBSERVATIONAL
Enrollment
100
The depth of anesthesia will be monitored using Bispectral Index values.
Regional Institute of Gastroenterology and Hepatology "Prof.Dr.O.Fodor"
Cluj-Napoca, Cluj, Romania
RECRUITINGPrediction model for postoperative delirium (POD) in major abdominal surgery
Developing an accesible algorithm to anticipate the occurence of postoperative delirium, based on functional baseline and proteomics, in adult patients subjected to major abdominal surgical interventions. This includes investigating a correlation between a set of risk factors, a panel of biomarkers and the occurrence of postoperative delirium in the enrolled patients, respectively.
Time frame: 3-4 years
Anesthesia depth monitoring and the incidence of postoperative delirium
Assessing the influence of BIS monitoring during general anesthesia on the prevalence of postoperative delirium
Time frame: 0-4 days postoperatively
Postoperative delirium incidence in surgical patients in the Intensive Care Unit (ICU) setting
Time frame: during ICU hospitalization
Postoperative delirium incidence in surgical patients - subgroup - communism survivors
Time frame: during ICU hospitalization
Postoperative delirium incidence in surgical patients - subgroup - patients with no relatives/visitors
Time frame: during ICU hospitalization
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