Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality all over the world. Smoking is considered as an important risk factor, but other risk factors are present. Around 30 % of patients with COPD are non-smokers. Cessation of smoking in patients with COPD causes decreases the presence of micronodules and other criteria of CT chest. In last few years, some researchers reported that cessation of smoking raise the apparent extent of emphysema. The cause is not obvious, but this paradoxical fall in lung density is thaught to be resulting from decrease in inflammation after smoking cessation. CT chest criteria of COPD in active smokers, non-smokers and ex-smokers seem to be different. So, comparison between CT chest Criteria of COPD in smokers, ex-smokers and non-smokers will be searched in this study to detect the role of multislice computed tomography (MSCT) chest in differentiation between COPD patients according to their smoking status.
Basic ethical principles of medical research; beneficence (do well), non-maleficence (do no harm), respect and distributive justice were implemented. The study will be carried out in accordance with the Declaration of Helsinki and the principles of good clinical practice.
Study Type
OBSERVATIONAL
Enrollment
90
Multi slice Computed Tomography of the chest
Number of participants with criteria of severe COPD
Criteria of severe COPD include emphysematous bullae, thick bronchial walls.
Time frame: 18 months
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