Patients With Asymptomatic Hyperuricemia Have Stronger Local Inflammatory Response and Worse Outcome After Total Knee Arthroplasty

Second Affiliated Hospital, School of Medicine, Zhejiang University614 enrolled

Overview

We identify all patients who had undergone primary total knee arthroplsty(TKA) from April 1, 2015, to March 30, 2016. Patients are grouped by uric acid level. The knee society score(KSS score) and the hospital for special surgery knee score (HSS score) before the surgery and 6 years after the surgery will be collected. Also the clinical data will be collected.

Study Type

OBSERVATIONAL

Enrollment

614

Conditions

Arthritis Knee

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * patients who had undergone primary TKA from April 1, 2015, to March 30, 2016 Exclusion Criteria: * (1) infection, (2) rheumatoid arthritis, (3) ankylosing spondylitis, (4) revision surgery, (5) patients with unicondylar knee replacement, (6) patients who have been diagnosed with gout or previous gouty symptoms, and (7) patients combined with preoperative redness or swelling.

Outcomes

Primary Outcomes

CRP

C-reactive protein

Time frame: within 7 days after surgery

temperature

The nurses measured the body temperature by Non-contact Ear Thermometer. The temperatures were measured at 6 am, 14 pm, and 18 pm every day, and the patients were kept admitted till day 5. The highest one was chosen for analysis.

Time frame: within 7 days after surgery

HSS score

the hospital for special surgery knee score

Time frame: 6 years after surgery

KSS scores

knee society score

Time frame: 6 years after surgery

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.