Cannabinoid vs Opioid for Photorefractive Keratectomy Pain Control

Inclusion Criteria: * Adults older than 18 years with refractive stability for 1 year electing to have PRK surgery * Consenting to participate * Not meeting exclusion criteria will be included in the study population. Exclusion Criteria: * Patients not candidates for PRK will be excluded from the study. * Patients taking other pain medications for concomitant medical conditions including, but not limited to tricyclic antidepressants, gabapentin and tramadol will be excluded from the study. * Additional exclusion criteria will be known or suspected allergy or hypersensitivity to any of the routine or study medications. * Patients completing follow up appointments at anywhere other than UF Health Ophthalmology clinic at the Oaks will not be enrolled in the study. * Patients who are pregnant or nursing are not eligible for PRK, and such patients are not eligible to enroll in this study. Female patients of child-bearing age will be pregnancy tested before surgery and study enrollment. * Patients will be specifically counseled, and it will be noted in the written informed consent that use of the cannabinoid product may result in a positive THC urinalysis screening test so they may self-exclude if such a situation could cause social and/or employment conflict.