Prevention or Treatment of Arterial Hypotension and Oxygen Cerebral Saturation During Major Abdominal Surgery

Fondazione Policlinico Universitario Agostino Gemelli IRCCS48 enrolled

Overview

In this study investigators will explore the association between intraoperative arterial hypotension and cerebral oxygen saturation in patients scheduled for major abdominal surgery. Investigators will assign patients to control or interventional group. In this last group arterial hypotension will be avoided based on a HPI (Hypotension Predictive Index) protocol. In the control group arterial hypotension will be promptly treated according to hemodynamic variables.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Hypotension During Surgery Hemodynamic Instability

Interventions

Eligibility

Sex: ALLMin age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients scheduled for abominal surgery Exclusion Criteria: * Emergency surgery * end-stage renal disease * pregnancy * obesity * atrial fibrillation * previous cerebral ischaemia * central nervous system disorders

Outcomes

Primary Outcomes

Cerebral tissue oximetry

the difference among the two groups of the percentage value of the median value of Cerebral Oxygen Saturation measured by the near-nfrared spectroscopic technology (Foresight sensor)

Time frame: immediately after surgery