Childhood obesity is a significant public health concern worldwide. In China, childhood obesity has dramatically increased as the economy has grown quickly over the past decades. Nonalcoholic fatty liver disease (NAFLD) is tightly associated with obesity, in China, the prevalence of NAFLD in obesity children is 40.0%,the main interventions for NAFLD are lifestyle interventions. Effective strategies to helping students lose weight and alleviate NAFLD through lifestyle interventions may help promote the physical and mental health of obese students. This study aimed (1)to assess the effectiveness of the intervention compared with the usual practice in treating childhood overweight and obesity; (2) to determine the sustainability of the treatment in preventing overweight and obesity; (3) to help alleviate or reverse NAFLD in obesity children. Children with overweight and obesity in six primary schools in Ningbo City, Zhejiang Province will be seleted and randomly divided into two groups: the treatment group and the usual practice group. The participants of the study were students in the third grade of primary school, and the treatment will last for one academic year. This treatment activity on lifestyle interventions will target the dietary and exercise factors of childhood obesity.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
331
This intervention programme will target the influencing factors of childhood obesity to influence the knowledge, attitude and behaviours of school children. Students in the treatment group will receive the following interventions: * Develop and implement school policies related to weight loss * Distribute health education materials on diet and exercise to students * Carry out student health education courses * Diet and exercise instruction by professional nutritionist using internet applet * Take part in sports activities that are organized by the sports health teacher during school hours.
Ningbo First Hospital
Ningbo, China
change in body mass index (BMI)
* weight and height will be combined to report BMI in kg/m\^2 * caculated by terminal value minus baseline value
Time frame: 3 months,9 months , 24 months and 36 months
change in controlled attenuation parameters (CAP)
* CAP will be detected by Fibroscan * caculated by terminal value minus baseline value
Time frame: 3 months,9 months , 24 months and 36 months
Change in liver stiffness measurement (LSM)
* LSM will be detected by Fibroscan * caculated by terminal value minus baseline value
Time frame: 3 months,9 months , 24 months and 36 months
Change in BMI z- score
* BMI z- score are measures of relative weight adjusted for child age and sex * caculated by terminal value minus baseline value
Time frame: 3 months,9 months , 24 months and 36 months
change in blood glucose
caculated by terminal value minus baseline value
Time frame: 9 months
change in blood lipids
* include TC, TG, LDL-C, HDL-C * caculated by terminal value minus baseline value
Time frame: 9 months
change in fasting insulin
caculated by terminal value minus baseline value
Time frame: 9 months
change in body fat percentage
caculated by terminal value minus baseline value
Time frame: 3 months and 9 months
change in waist circumference
caculated by terminal value minus baseline value
Time frame: 3 months,9 months , 24 months and 36 months
change in weight
caculated by terminal value minus baseline value
Time frame: 3 months,9 months , 24 months and 36 months
change in cardiorespiratory endurance test
caculated by terminal value minus baseline value
Time frame: 3 months,9 months , 24 months and 36 months
change in ALT(alanine transaminase)
caculated by terminal value minus baseline value
Time frame: 9 months
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