Moderate Sedation Combined With Acupuncture Anesthesia in Gastroscopy and Colonoscopy on Screening Research

The Affiliated Hospital of Qingdao University108 enrolled

Overview

The purpose of this study is mainly about the feasibility and rationality of moderate sedation combined with acupuncture anesthesia in the application of gastroscopy and colonoscopy ,Then we evaluate the effectiveness and advantages of the combination of acupuncture anesthesia and drug anesthesia.

With the increase of the proportion of the patients who crave for performing painless gastroscopy and colonoscopy in recent years, it is crucial to seek a more secure and effective method of anesthesia or sedation. At present, the universal anesthetic method on gastroscopy and colonoscopy in China is the general anesthesia without intubation which usually uses propofol and opioid analgesics,Although the satisfaction of patients is high, the incidence of anesthesia-related complications and drug-related adverse reactions is high .The incidence of adverse events during the gastroscopy and colonoscopy is high, and the medical expense of anesthesia is high. At present, more than 2/3 of the patients undergo painless gastroscopy or colonoscopy are middle-aged and elderly patients, so the overdose which prolongs the recovery time、discharge time of patients and reduces the recovery quality of patients is common. The moderate sedation, which fundmentally does not affect hemodynamics、autonomous respiration and protective reflexes, is incomparable to general anesthesia . And acupuncture anesthesia also acts as a safe anesthetic method can provide safer analgesic effect.Theoretically，the combination of both of them is a relatively perfect and safe painless method.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

108

Conditions

Gastrointestinal Endoscopy

Interventions

fentanylDRUG

The investigator 1 use fentanyl to sedate patients coordinate with remimazolam

eletroacupuncture(transcutaneous electrical acupuncture point stimulation )PROCEDURE

The investigator 1 use electroacupunture(transcutaneous electrical acupuncture point stimulation )to coordinate with remimazolam

placebo needleDRUG

The investigator 1 use placebo needle to sedate patients coordinate with remimazolam

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Outpatients 2. Patients with ASA grade I-III 3. A sufficient level of education to understand study procedures and can communicate with investigators. Exclusion Criteria: 1. Patients with serious systemic diseases such as severe cardiopulmonary disease or hepatic diseases or renal diseases. 2. Patients under the age of 18. 3. Patients who did not sign the informed consent form. 4. Patients who have a history of alcohol abuse or drug abuse. 5. People who are allergic to anesthetic related ingredients, such as soybeans, eggs and so on. 6. Patients with extreme fear or anxiety about acupuncture. 7. Patients with relative contraindications of gastrointestinal endoscopy. \-

Locations (1)

Jixiangyu

Qingdao, Shandong, China

Outcomes

Primary Outcomes

patient satisfaction with sedation instrument，PSSI

The investigator 2 needs to use VAS scores to evaluate satisfaction about sedation feeling when they accepted gastroscopy and colonoscopy .The score ranges from 0 to10 and need patients evaluate it by themself when the gastroscopy or colonoscopy were finished.The score from 0 （extremely dissatisfied）to 10（extremely satisfied）.