The aim of this study is to explore the diagnostic efficacy of oral glucose tolerance test in early pregnancy and establish the prediction model for gestational diabetes mellitus, so as to provide the optimal screening of gestational diabetes mellitus in the first trimester. The treatment started when the pregnancy was confirmed by transvaginal ultrasound (around 6 weeks of gestation) and continued until 42 days postpartum. The study is a single center, prospective cohort study. A total of 781 participants within 14 weeks of gestation were recruited.
Study Type
OBSERVATIONAL
Enrollment
781
The exposure means the hyperglycemia identified by the 75g oral glucose tolerance test before the 14 weeks of gestation
Women's Hospital School of Medicine Zhejiang University
Hangzhou, Zhejiang, China
gestational diabetes mellitus
any of the fasting, 1-hour and 2-hour blood glucose ≥ 5.1, 10.0, 8.5 mmol/L, respectively, in the 75g oral glucose tolerance test during 24-28 weeks of gestation
Time frame: 24-28 weeks of gestation
gestational weight gain
total weight gain from pre-pregnancy until delivery
Time frame: before delivery
gestational age at delivery
gestational weeks at the day of delivery
Time frame: through study completion, an average of 39 gestational weeks
birthweight
birthweight of the infant
Time frame: within 24 hours after birth
neonatal weight, height and head circumference
baby's weight, height and head circumference at 42 days after birth
Time frame: 42 days after birth
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.