Management in Intensive Care Unit of Life-threatening Keto-Acidosis

Inclusion Criteria: * Major (age ≥ 18 years old) * Hospitalized in intensive care between January 2014 and December 2023 for ketoacidosis complicated by organ failure in the participating departments. * Diagnosis of ketoacidosis judged to be the main cause of the severity of the clinical condition. * Blood potential hydrogen \< 7.15 and bicarbonates \< 10mmol/L in the first 12 hours of treatment. * Presenting at least one of the 3 organ failures during hospitalization among: * Use of extra-renal purification for acute renal failure * Administration of pressor amines * Use of mechanical ventilation Exclusion Criteria: * Metabolic acidosis primarily of an origin other than ketonic * Refusal to participate or opposition to the processing of their data * Patient under guardianship or curators