Acute kidney injury (AKI) has been recognized as a typical post- operative complication among the children undergoing surgical repair of a congenital cardiac defect. It is associated with increased morbidity and mortality in the intensive care unit and a higher utilization of hospital resources. However, how to precisely identify those who have greater hazard to encounter postoperative AKI seems ambiguous.
The development of AKI is common following cardiac surgery whether in adult or pediatric population. Not only severe AKI like dialysis support, but also mild kidney injury has profound influence on increased subsequent morbidities and mortality. Pediatric patients who undergo cardiac procedures are characterized by lower weight, younger age, complicated cardiac anomaly and poor resistance to surgical insults. Thus, in comparison with adults, their AKI risk is relatively higher. At present there has been no specific intervention regarding AKI prevention and therapy. Establishing a risk score based on patient characteristics and surgical information to effectively predict postoperative AKI risk is therefore imperative. It can serve as a decision-making tool to facilitate patient management with regard to kidney prognosis. This program is aimed at developing and internally validating a AKI risk score post cardiac surgery in a Chinese pediatric population.
Study Type
OBSERVATIONAL
Enrollment
2,000
No intervention
Fuwai Hospital
Beijing, Beijing Municipality, China
RECRUITINGThe Prevalence of Acute Kidney Injury
Acute Kidney Injury was defined by Kidney Disease Improving Global Outcomes (KDIGO) Criteria. Accordingly, AKI was classified as stage 1, stage 2 and stage 3.
Time frame: Up to postoperative 7 days
The incidence of dialysis
The therapeutic approach to correct renal failure
Time frame: Up to postoperative 7 days
The hours of mechanical ventilation
Time before first extubation
Time frame: Up to postoperative 7 days
The incidence of reinbutation
Need for postoperative endotracheal intubation given the occurrence of respiratory or non-respiratory complication after extubation.
Time frame: Up to hospital discharge, an average of 7 days
The incidence of tracheotomy
The necessary treatment for postoperative respiratory failure
Time frame: Up to hospital discharge, an average of 7 days
The incidence of re-operation
Re-exploration prescribed by surgeons due to cardiac issues or excessive chest drainage volume.
Time frame: Up to hospital discharge, an average of 7 days
The incidence of mechanical cardiac support
Supported by extracorporeal membrane oxygenation from operative day to discharge or death
Time frame: Up to hospital discharge, an average of 7 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
The incidence of mortality
Specific death reason
Time frame: Up to hospital discharge, an average of 7 days
The incidence of pulmonary infection
Assessed by relevant guidelines of pulmonary infection
Time frame: Up to hospital discharge, an average of 7 days
The cost of medical resources
The RMB patients spend during the whole hospitalization
Time frame: Up to hospital discharge, an average of 7 days
Intensive Care Unit Discharge Time
Time and date when the patient is transferred to ward
Time frame: Up to ICU discharge, an average of 5 days
Hospital Discharge Time
Time and date when the patient is discharged from the hospital
Time frame: Up to hospital discharge, an average of 7 days
The relative change of left ventricular ejection fraction (LVEF) from baseline to hospital discharge
(LVEF at hospital discharge - LVEF at baseline)/LVEF at baseline \* 100%
Time frame: Up to hospital discharge, an average of 7 days
The relative change of left ventricular end-diastolic diameter (LVEDD) from baseline to hospital discharge
(LVEDD at hospital discharge - LVEDD at baseline)/LVEDD at baseline \* 100%
Time frame: Up to hospital discharge, an average of 7 days