The main objectives of this imaging biomarker study are to assess the annual lung function change in patients with progressive fibrosing interstitial lung disease (PF-ILD) including idiopathic pulmonary fibrosis (IPF), with Usual Interstitial Pneumonia (UIP) or probable UIP Computer Tomography (CT) pattern, and to monitor lung structural changes.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
31
Pulmonary function test
Pulmonary function test
Magnetic Resonance Imaging
Medizinische Hochschule Hannover
Hanover, Germany
Absolute change in Forced Vital Capacity (FVC) % predicted from baseline to week 52
Time frame: at baseline and at week 52
Absolute change in fibrosis extent in % of lung volume determined on chest Computer Tomography (CT) from baseline to week 52
Time frame: at baseline and at week 52
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Chest Computer Tomography
Blood biomarker analysis