There are more than 75% of patients with gastric cancer who are diagnosed in advanced stage in Vietnam, most of cases in T4a. The purpose of this study was to compare short- and long- term outcomes of open and laparoscopic distal gastrectomy for gastric adenocarcinoma in surgical T4A stage.
Gastric cancer is one of the most common cancers in Vietnam . Despite recent advances in multimodality treatment and targeted therapy, surgery remains the first option of treament for this disease. For resectable gastric cancer, complete removal of macroscopic and microscopic lesions and/or combined resections and also regional or extended lymphadenectomy should represent worldwide now. Laparoscopic gastrectomy for locally advanced gastric cancer AGC have commonly used for treatment of AGC, especially in Japan, Korea and China. However, the real role of laparoscop for treament of (AGC) is still controversial in term of technical feasibility, safety and oncologic aspect for T4a stage. Paragastric inflammatory strands may occur in T4a tumor so that laparoscopic technique is difficult to radically perform. Peritoneal seeding of malignant cells, intra- and postoperative complications, trocarts metastasis may risk during procedures. Despite, some studies have demonstrated the safety and the short-term benefits of LG for T4a gastric cancer, the number of these studies and sample sizes have been still inadequate to give good evidence for applying it. and long-term oncologic outcomes There are more than 75% of patients with gastric cancer who are diagnosed in advanced stage in Vietnam, most of cases in T4a. The purpose of this study was to compare short- and long- term outcomes of open and laparoscopic distal gastrectomy for gastric adenocarcinoma in surgical T4A stage.
Study Type
OBSERVATIONAL
Enrollment
472
Distal gastrectomy and standard D2 lymphadenectomy
University Medical Center Ho Chi Minh City
Ho Chi Minh City, Vietnam
5 year overall survival by Kaplan Mayer
The percentage of people in this study who are alive five years after surgery.
Time frame: 5 year after surgery
5 year disease-free survival by Kaplan Mayer
The percentage of people in this study who are alive without recurrence/metastasis five years after surgery.
Time frame: 5 year after surgery
1 year overall survival by Kaplan Mayer
The percentage of people in this study who are alive one years after surgery.
Time frame: 1 year after surgery
3 year overall survival by Kaplan Mayer
The percentage of people in this study who are alive one years after surgery.
Time frame: 3 year after surgery
1 year disease-free survival by Kaplan Mayer
The percentage of people in this study who are alive without recurrence/metastasis one years after surgery.
Time frame: 1 year after surgery
3 year disease-free survival by Kaplan Mayer
The percentage of people in this study who are alive without recurrence/metastasis one years after surgery.
Time frame: 3 year after surgery
operative morbidity
The overall rate of postoperative complications
Time frame: 30 days after surgery
operative time
The duration of a surgical procedure in minutes.
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Time frame: intraoperative
operative blood loss
The amount of blood lost during procedure
Time frame: intraoperative
time to flatus
Number of days from date of surgery until date of flatus
Time frame: 30 days after surgery or until mortality ]
Postoperative hospital length of stay
Number of days from date of surgery until date of discharge or mortality
Time frame: 30 days after surgery or until mortality
The percentage of complications with Clavien-Dindo
The percentage of complication grade by Clavien-Dindo classification
Time frame: 30 days after surgery
The percentage of pattern of recurrence/metastasis
The percentage of pattern of recurrence/metastasis during follow up period
Time frame: 5 year after surgery