The patients who accepted the quadruple eradication program of the helicobacter pylori but failed to eradicate helicobacter pylori will be assessed the most suitable re-eradication time of helicobacter pylori.
Helicobacter pylori (HP) infection is a common global infectious disease, which is an important cause of chronic gastritis, peptic ulcer and gastric cancer. At present, due to the non-standard Helicobacter pylori eradication program in clinical work, poor patient compliance and other reasons, the phenomenon of HP eradication treatment failure is more and more common. However, there is still no conclusion on the most appropriate time for remedial treatment inpatients with Hp eradication failure.
Study Type
OBSERVATIONAL
Enrollment
660
Remedial therapy was performed within 3 months
Remedial therapy was performed within 3 to 6 months
Remedial therapy was performed within 6 to 12 months
The most suitable re-eradication time
The most suitable re-eradication time#The unit is month# will be assessed by paired comparison method .
Time frame: 12 months
Eradication rates in three groups
Both intention to treat(ITT) and per-protocol(PP) analyses will be used for the assessment of the eradication rates of Helicobacter pylori infections in three groups
Time frame: 12 months
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Remedial therapy was performed after 12 months