This study aims to analyse retrospectively the feasibility, the safety, and the efficiency, of biliary or digestive protection with room air interposition for thermal ablation of central liver tumors with high iatrogenic risk. Thermal ablation is a mini-invasive and curative treatement of liver tumors. However, it requires to be carefull about surrunding organs, such as digestive structures or central biliary tree, which can be injured if not insulated. The technique of gas interposition to protect adjacent gut is already known and validated with carbonic gas. Nevertheless, resorption of this gas is very fast, making its use tricky to keep a correct insulation during the whole thermal ablation process. Room air interposition is easy to use and can offer a slow resorption speed. Furthermore no datas are available concerning the use of room air whatever the organ protected, and the protection of central biliary tree whatever the gas used.
Study Type
OBSERVATIONAL
Enrollment
61
Data collection about complications, succes of the procedure, succes of complete treatement, recurrence, biologic pertubations.
CHU de Nice
Nice, France
Feasability
Technical succes of the procedure = feasibility of insulation with room air
Time frame: 1 day
Security
Complications (intraoperative clinical or radiological event/abnormality, biological perturbation, clinical event in hospitalization report, imaging request), classified according to SIR (Society of Interventional Radiology) classification in two classes: minor (no additional therapy needed) and major (specific therapy needed) complications.
Time frame: 2 months
Efficacity
Response in imaging (MRI or CT) for the tumor treated with thermal ablation
Time frame: 2 months
Clinical success
Overall survival
Time frame: 2 months
Local and distant recurrence
1. Local recurrence: defined by MRI or CT recurrence within 10 mm from thermal ablation area 2. Distant recurrence: I. Hepatic: defined by MRI or CT intra-hepatic recurrence which is not defined as local recurrence II. Extrahepatic: defined by MRI or CT extra-hepatic recurrence
Time frame: 2 months
Local tumorous recurrence free survival
Local tumorous recurrence free survival analysis
Time frame: 2 months
Progression free survival
Local or distant recurrence free survival analysis
Time frame: 2 months
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