The Ultrasonographic Changes of Intercostal Muscles and Diaphragm in Mechanically Ventilated Preterm Neonates

Noha Saied Ibrahim30 enrolled

Overview

Invasive mechanical ventilation induces ventilator induced diaphragmatic dysfunction particularly when used for long time and Intercostal muscles as well contribute to the important work of respiratory movement by expanding the thorax , and determining the thickness of them would be a useful parameter in evaluating respiratory muscle activity. This study will add the impact of mechanical ventilation on the diaphragm and intercostal muscles in preterm infants using ultrasound.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Mechanical Ventilation Complication

Eligibility

Sex: ALLMin age: 5 MinutesMax age: 28 Days

Medical Language ↔ Plain English

Inclusion Criteria: 1. Preterm infants from 28-36 weeks gestation 2. In need for invasive mechanical ventilation according to work of breathing, oxygen saturation and blood gases . Exclusion Criteria: * 1\) Significant congenital anomalies including cardiac, abdominal or respiratory. 2\) Congenital anomalies involving the diaphragm. 3) Phrenic nerve paralysis. 4) Congenital muscular dystrophies. 5) Major upper or lower airway anomalies. 6) Storage diseases.

Locations (1)

Ain Shams University

Cairo, Egypt

RECRUITING

Outcomes

Primary Outcomes

The impact of mechanical ventilation on diaphragm and intercostal muscles using ultrasound

Using Ultrasound to measure Intercostal Muscles thickness and diaphragmatic thickness and excursion for assessing the impact of the mechanical ventilation on muscle power predicting weaning from ventilation.

Time frame: 6 months

Central Contacts

Noha Ibrahim, MB, BCh

CONTACT

01064099564 Nohasaied2000@gmail.com

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.