Study of the Prognosis of Patients With Heart Failure With Preserved Ejection Fraction

Chongqing Medical University172 enrolled

Overview

Study of the prognosis of patients with heart failure with preserved ejection fraction

Obesity is an independent risk factor for heart failure with preserved ejection fraction (HFpEF), however, the impact of visceral fat area (VFA) in patients with HFpEF is unclear. According to established process of patients' selection, a total of 172 patients whose mean age was 72 years were included in this study, and the median follow-up duration was 395.5 days(interquartile range: 207.5 to 535.5 days). All patients were divided into two groups based on the best cut-off value of VFA, and the primary outcome of this study was all-cause death in patients with HFpEF. The aim of this study was to clarify whether VFA has prognostic value in patients with HFpEF by Kaplan-Meier analysis and cox analysis.

Study Type

OBSERVATIONAL

Enrollment

172

Conditions

Heart Failure With Preserved Ejection Fraction

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Adult aged \>=18years old; 2. Diagnosed with HFpEF.Diagnostic criteria including: 1）left ventricular ejection fraction ≥50%； 2）with the symptoms and/or signs of heart failure； 3）BNP≥35 pg/mL and/or NTproBNP≥125 pg/mL； 4）at least one additional criterion: relevant structural heart disease(LVH and/or LAE) or diastolic dysfunction Exclusion Criteria: 1. Age \<18 years old； 2. LVEF less than 45% at any time; 3. cancer diagnosis.

Locations (1)

The First Affiliated Hospital of Chongqing Medical University

Chongqing, China

Outcomes

Primary Outcomes

death

all-cause death

Time frame: The median follow-up time of 395.5 days(interquartile range: 207.5 to 535.5 days)

Data from ClinicalTrials.gov

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