This randomized trial will compare the efficacy of two different times of administration of medications for final oocyte maturation, commonly called a "trigger", in cycles of controlled ovarian stimulation (COS) for cycles in which all embryos will be cryopreserved ("freeze-all cycles").
This randomized trial will compare the efficacy of two different times of administration of medications for final oocyte maturation, commonly called a "trigger", in cycles of controlled ovarian stimulation (COS) for cycles in which all embryos will be cryopreserved ("freeze-all cycles"). 1. The early trigger timing will be based on sonographic observation of at least three follicles reaching at least 17mm in diameter. 2. The delayed trigger timing will be based on at least three follicles reaching at least 22mm in diameter.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
150
Timing of medication to induce final oocyte maturation
Fertility center of Las Vegas
Las Vegas, Nevada, United States
RECRUITINGGood-quality blastocysts
Number of blastocysts with A or B morphological grade.
Time frame: Within 7 days of oocyte retrieval
Delayed blastocyst formation
Proportion of good-quality of blastocysts that formed after day 5.
Time frame: Within 7 days of oocyte retrieval
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