The Effect of Gallstone Characteristics for the Severity of Gallstone Pancreatitis

Hepatopancreatobiliary Surgery Institute of Gansu Province301 enrolled

Overview

The purpose of this study was to determine the effect of gallstone characteristics for the severity of acute gallstone pancreatitis (GSP)

The timing of cholecystectomy is closely related to the severity of acute gallstone pancreatitis (GSP). The effect of gallstone characteristics (including stone size, number, etc.) for the severity of GSP are currently unknown.

Study Type

OBSERVATIONAL

Enrollment

301

Conditions

Acute Gallstone Pancreatitis

Interventions

Gallstone characteristicsOTHER

stone size, number, the thickness

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Acute gallstone pancreatitis (GSP) patients. Exclusion Criteria: * Pancreatitis with bile duct stones, trauma, drugs, and surgery; * Recurrent gallstone pancreatitis; * Combined with other malignant tumors, such as liver cancer, cholangiocarcinoma, pancreatic cancer, gastric cancer, Hematologic tumor, and lymphoma; * Previous hepatobiliary and pancreatic surgery, Organ transplantation; * Intestinal obstruction or other obstructive diseases; * Chronic pancreatitis or pancreatic duct stones; * Thrombotic disease; * Alcoholic pancreatitis and hyperlipidemia pancreatitis.

Locations (1)

Hepatopancreatobiliary Surgery Institute of Gansu Province

Lanzhou, Gansu, China

Outcomes

Primary Outcomes

Number of severity of GSP patients

Based on the 2012 Atlanta International Consensus, Mild acute pancreatitis (MAP) is defined as no organ failure and no local or systemic complications. Moderate to severe acute pancreatitis (MSAP) refers to patients with organ failure, local complications, or aggravated complications. Severe acute pancreatitis (SAP) is defined as persistent organ failure for more than 48 hours.

Time frame: 1 month

Secondary Outcomes

Modified computed tomography severity index (MCTSI) score

Without knowing the prognosis, two radiologists with eight and ten years of experience independently scored the severity of GSP through the MCTSI score and reached an agreement through discussion when there was disagreement.

Time frame: 1 month

Gallstone size

The diameter of the stones

Time frame: 1 month

Number of stones

The number of gallstones

Time frame: 1 month

Data from ClinicalTrials.gov

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