Nonspecific low back pain is one of the most common health problems today. Although it is encountered so frequently, the relationships between the symptoms of patients who complain of low back pain have not been fully explained. With pain, changes occur in the body of individuals. When the blood values of individuals are examined, changes are observed in their biomarkers. Two of these biomarkers are anti-inflammatory and pro-inflammatory biomarkers. These two biomarkers indicate that there is an inflammation in the body. Inflammation can cause pain. Pain also prevents individuals from performing their movements correctly and can cause individuals to make biomechanical changes in their bodies that will make them feel less pain. Clinicians and physiotherapists treat symptoms for pain, patients' pain starts again or does not go away at all because the underlying problem is not fully understood and resolved. Biomechanical features that can be explained as muscle activation and joint movements can be defined as the lowest unit of functional movement. These movements combine to form functions. When we search for functionality in the literature, we see that the functionality increases with the decrease of inflammation. Functions performed in a different way than normal due to pain and changes in these functions may or may not be at an observable level. For this reason, the biomechanical changes of individuals with pain will be analyzed with a more detailed and objective measurement system. The three-dimensional motion analysis system and muscle activation measuring devices to be used in this study are devices that can make the most accurate and precise measurement and allow us to examine the lowest unit of motion. This study will go to the basis of the movement and understand the problems there and will contribute to the production of permanent solutions in future studies. Pain and biomarkers and pain and biomechanical properties were evaluated separately in the studies, no study was found that examined biomechanical properties and biomarkers together. The aim of the project is to examine the relationship between inflammation and biomechanical properties. At the end of the project, the relationship between inflammation and biomechanical changes in low back pain will be demonstrated objectively, and it is anticipated that new treatment strategies can be developed for nonspecific low back pain.
Study Type
OBSERVATIONAL
Enrollment
42
Participants with nonspesific low back pain and control group will be analysed with 3D motion analysis sistem, sEMG and will be checked the biomarkers. Then the data will be compared.
Motion analysis
Noraxon MyoMotion 3D motion analysis system will be used. Inertial measurement unit (IMU) are placed on any body segment with elastic fixation straps. The sensors will be placed in the spinal processes of Thoracic 12, Lumbar 3 and Sacral 2 with adjustable straps. The participant is asked to stand while placing the sensors. T12 level is found by palpating the spinal processes of the spines. Sacral 2 spinal process is palpated from line between right and left posterior superior spina iliaca. efore each measurement, the IMU sensors will be calibrated for body position. Data collected with a sampling frequency of 200 Hz will be recorded. A laptop camera will be used as a camera during the measurements.
Time frame: baseline
Muscle activation
Noraxon MyoMuscle system will be used. The MyoMuscle system processes the signals sent by superficial electromyography (sEMG) electrodes placed on the participants' body. The electrodes used in sEMG measurement are Ag/AgC superficial electrodes. In the EMG analysis, 2 muscle groups will be evaluated, and the electrodes will be placed bilaterally. Lumbal erector spines: Electrodes is placed 3 cm lateral to the spinal process of the fourth lumbar spine. Obliquus internus: The electrode is placed 2 cm medial to the anterior superior iliac spine. The signals of muscle movements of the electrode-placed muscles during standing up from sitting will be measured. TeleMyo DTS will be used to collect EMG data. Collected data will be filtered by MyoResearch XP 1.72 software.
Time frame: baseline
Short Form McGill Pain Questionnaire
The McGill Pain Questionnaire consists of a total of 15 descriptive words. Of the 15 words used to evaluate the dimensions of pain, 11 are used to evaluate the sensory and 4 are used to evaluate the affective dimensions of pain. Pain intensity is scored by the patient as 0=absent, 1=mild, 2=moderate, 3=severe. Total scores are scored at three levels: sensory, affective, and total (sensory+affective). The Short Form McGill questionnaire has a visual analog scale used to assess the severity of pain and a 6-point Likert scale. In the Likert scale of SF- McGill index, 0 = no pain, 1 = mild, 2 = bothersome, 3 = distressing, 4 = awful, 5 = excruciating pain.
Time frame: baseline
Analysis of Inflammatory Markers (Interleukin-1Beta, Tumor Necrosis Factor Alpha, Interleukin-6, Interleukin-2, Interleukin-8, Interleukin-10 )
Changes between individuals with low back pain and healthy individuals.
Time frame: baseline
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