The purpose of this study is to learn about the change in quality of sleep, structural organization of sleep, and cardiovascular responses after consuming an energy drink compared to a placebo drink with no caffeine or stimulants.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
54
Two 16-oz energy drinks consumed orally to be finished approximately 4 hours prior to bed
Two 16-oz identical looking placebo drink without caffeine consumed orally to be finished approximately 4 hours prior to bed
Mayo Clinic Rochester
Rochester, Minnesota, United States
Changes in sleep efficiency
Time asleep / time in bed
Time frame: Throughout duration of sleep on both nights (night 1 and night 2)
Changes in sleep continuity
Frequency of wakefulness after sleep initiation
Time frame: Throughout duration of sleep on both nights (night 1 and night 2)
Changes in sleep architecture
Time spent in each stage of sleep
Time frame: Throughout duration of sleep on both nights (night 1 and night 2)
QT segment
QT duration
Time frame: Baseline, approximately 1 hour prior to energy drink consumption
QT segment
QT duration
Time frame: Throughout duration of sleep on both nights (night 1 and night 2)
Atrial arrhythmias
Frequency of ectopic atrial beats
Time frame: Baseline, approximately 1 hour prior to energy drink consumption
Atrial arrhythmias
Frequency of ectopic atrial beats
Time frame: Throughout duration of sleep on both nights (night 1 and night 2)
Ventricular arrhythmias
Frequency of ectopic ventricular beats
Time frame: Baseline, approximately 1 hour prior to energy drink consumption
Ventricular arrhythmias
Frequency of ectopic ventricular beats
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Time frame: Throughout duration of sleep on both nights (night 1 and night 2)
Sympathetic activation quantified by changes in plasma norepinephrine
Plasma norepinephrine while supine
Time frame: Baseline and AM of day 2
Sympathetic activation quantified by changes in plasma epinephrine
Plasma epinephrine while supine
Time frame: Baseline and AM of day 2
Sympathetic activation quantified by changes in plasma dopamine
Plasma dopamine while supine
Time frame: Baseline and AM of day 2
Sympathetic activation quantified by urine norepinephrine
Total urine norepinephrine secretion
Time frame: Approximately 24 hours
Sympathetic activation quantified by urine epinephrine
Total urine epinephrine secretion
Time frame: Approximately 24 hours
Sympathetic activation quantified by urine dopamine
Total urine dopamine secretion
Time frame: Approximately 24 hours