The aim of this study is to investigate the influence of four different ambient temperatures (18, 22, 28, 38°C) on the resting energy expenditure of healthy adults by respiratory gas analysis. It is assumed that the resting energy expenditure is higher at 18°C and 38°C than at the temperatures in between.
In a crossover-design, 32 healthy men and women participate in four interventions. Each intervention includes a measurement of the resting energy expenditure by respiratory gas analysis at a different ambient temperature (18,22, 28 and 38°C). During this time body core- and surface temperature are assessed, as well as body composition via bioelectrical impedance analysis. For each participant the four individual study days take place in a randomized order on consecutive weekdays within a week.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
32
Respiratory analysis at an ambient temperature of 18°C
Respiratory analysis at an ambient temperature of 22°C
Respiratory analysis at an ambient temperature of 28°C
University of Bonn
Bonn, Germany
Resting Energy Expenditure
Volume of inhaled oxygen (VO2) in L/min and exhaled carbon dioxide (VCO2) in L/min
Time frame: 20 minutes
Body core temperature
Body core temperature: assessed every ten seconds during respiratory analysis (°C)
Time frame: 20 minutes
Body surface temperature
Body surface temperature: assessed every ten seconds during respiratory analysis (°C)
Time frame: 20 minutes
Body composition
assessed daily via bioelectrical impedance analysis after respiratory analysis (FFM (kg), FM (kg))
Time frame: 5 minutes (after respiratory analysis)
Blood pressure
assessed daily before respiratory analysis (mmHg)
Time frame: 10 minutes (at beginning of study day)
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Respiratory analysis at an ambient temperature of 38°C