Regional anesthesia and analgesia technics are widely and securely used during orthopedic surgery. Interfascial plane blocks are the latest used ones for analgesia. There are studies in literature indicating that bupivacaine cause myotoxicity. We aimed to examine plasma CPK(creatine phosphokinase) levels to see whether myotoxicity occurs or not after suprainguinal fascial plane block is applied to patients undergoing knee artroplasty surgery.
During 2 months period all elligible patients undergoing knee artoplasty surgery will be included in the study. Different postoperative analgesic modalities will be used according to the anesthesists experience. During routine blood sample tests plasma CPK levels will be tested 3 times of all patients.(preoperative, postoperative 6th hour, postoperative 24th hour) this data will be recorded for 2 months. After this period of time data will be analysed and patients will be grouped according to the analgesic modalities used.
Study Type
OBSERVATIONAL
Enrollment
82
Suprainguinal fascia iliaca block will be performed after the end of surgery for postoperative analgesia.
Samsun University
Samsun, Turkey (Türkiye)
CPK levels
Change from Baseline serum creatine phosphokinase at 24 hours
Time frame: at postoperative 24th hour
Number of patients requesting rescue analgesics
Intravenous administration of meperidine 25 mg as a rescue analgesic is planned for patients who complain of severe pain despite multimodal analgesia.
Time frame: up to 24 hours
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