The study will examine the impact of the Nuun Sport tablets, as compared to water only, on heart rate, perceived exertion, and related outcomes in male and female runners, during and following the performance of a 60-minute treadmill run.
As discussed in our prior applications (protocol FY2020-327 and FY2021-96), maintaining adequate hydration is essential to optimal health (Perrier, 2017), as well as athletic performance (Nuccio et al., 2017). When individuals exercise (in particular in a warm environment), they can lose excessive amounts of fluids through sweating, along with necessary electrolytes (e.g., sodium, potassium, chloride). With dehydration, individuals may feel sluggish and can experience impaired physical performance. (Kenefick, 2018) Many attempts have been made to improve and measure the hydration status of active individuals (Love et al., 2018). This typically involves the ingestion of fluids leading up to activity (typically plain water), as well as the ingestion of fluids during the activity itself (water, along with a diluted carbohydrate/electrolyte beverage). During aerobic exercise, the shift in fluid (intake versus losses) can affect electrolyte balance, with dehydration and potential adverse effects on performance and health (Perrier et al., 2021; Armstrong et al. 2021). A better understanding of rehydration methods and resultant efficacy would permit selection by an athlete of the optimal method for preventing dehydration to optimize physical performance and reduce potential deleterious effects. It is well-accepted that electrolyte replenishment is of importance, both during and following exercise-to aid in rehydration for subsequent bouts. Electrolytes (sodium in particular) have been used for decades to aid athlete hydration and this has led to the development of various sport drinks-which also include small amounts of carbohydrate (e.g., Gatorade, Powerade). The present study will examine the impact of the Nuun Sport tablets, as compared to water only, on heart rate, perceived exertion, and related outcomes: changes in body mass, changes in plasma volume, post-exercise urine volume, and changes in urine specific gravity in male and female runners, during and/or following the performance of a 60-minute treadmill run.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
20
Subjects will consume a total of 24 ounces water and 1.5 tablets of Nuun SPORT. Specifically, subjects will drink 12 ounces of Nuun drink 15 minutes prior to the 60 min run and 4 ounces of Nuun drink at 15 min, 30 min, and 45 min during the run.
Subjects will consume a total of 24 ounces water. Specifically, subjects will drink 12 ounces of water 15 minutes prior to the 60 min run and 4 ounces of water at 15 min, 30 min, and 45 min during the run.
Center for Nutraceutical and Dietary Supplement Research
Memphis, Tennessee, United States
Heart rate
Heart rate will be measured before and every 10 minutes during the run using a chest strap
Time frame: baseline
Heart rate
Heart rate will be measured before and every 10 minutes during the run using a chest strap
Time frame: 10 minutes into run
Heart rate
Heart rate will be measured before and every 10 minutes during the run using a chest strap
Time frame: 20 minutes into run
Heart rate
Heart rate will be measured before and every 10 minutes during the run using a chest strap
Time frame: 30 minutes into run
Heart rate
Heart rate will be measured before and every 10 minutes during the run using a chest strap
Time frame: 40 minutes into run
Heart rate
Heart rate will be measured before and every 10 minutes during the run using a chest strap
Time frame: 50 minutes into run
Heart rate
Heart rate will be measured before and every 10 minutes during the run using a chest strap
Time frame: 60 minutes into run
Perceived exertion
Subjects will self-report perceived exertion using a scale from 0 (no exertion) to 10 (the most exertion)
Time frame: baseline
Perceived exertion
Subjects will self-report perceived exertion using a scale from 0 (no exertion) to 10 (the most exertion)
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Time frame: 10 minutes into run
Perceived exertion
Subjects will self-report perceived exertion using a scale from 0 (no exertion) to 10 (the most exertion)
Time frame: 20 minutes into run
Perceived exertion
Subjects will self-report perceived exertion using a scale from 0 (no exertion) to 10 (the most exertion)
Time frame: 30 minutes into run
Perceived exertion
Subjects will self-report perceived exertion using a scale from 0 (no exertion) to 10 (the most exertion)
Time frame: 40 minutes into run
Perceived exertion
Subjects will self-report perceived exertion using a scale from 0 (no exertion) to 10 (the most exertion)
Time frame: 50 minutes into run
Perceived exertion
Subjects will self-report perceived exertion using a scale from 0 (no exertion) to 10 (the most exertion)
Time frame: 60 minutes into run
Specific gravity of urine
Specific gravity will be determined from a urine sample
Time frame: baseline
Specific gravity of urine
Specific gravity will be determined from a urine sample
Time frame: 15 minutes after run
Plasma Volume
Plasma Volume will be determine via blood sampling and determination of hematocrit and hemoglobin
Time frame: baseline
Plasma Volume
Plasma Volume will be determine via blood sampling and determination of hematocrit and hemoglobin
Time frame: 5 minutes after run
Body Mass
Body Mass will be measured
Time frame: baseline
Body Mass
Body Mass will be measured
Time frame: 5 minutes after run
Body Mass
Body Mass will be measured
Time frame: 15 minutes post-run after urine collection
Urine output (mass)
Urine mass will be determine following collection
Time frame: 15 minutes post-run
Urine output (volume)
Urine volume will be determine following collection
Time frame: 15 minutes post-run