Feasibility of Thin Cp-EBUS Scope BF-UC290F for the Diagnosis of PPLs

Inclusion Criteria: * Patients older than 18 years old. * Chest imaging shows the presence of peripheral pulmonary lesions (surrounded by pulmonary parenchyma and located below the segmental bronchus as seen radiographically.) suspicious of malignancy, 0.8-5cm in greatest diameter in need of bronchoscopic biopsy for clinical purposes, and the investigators consider it possible to be biopsied with BF-UC290F (the bronchus adjacent or leading to the PPLs are close to 5mm in diameter, thus BF-UC290F is able to arrival/access). * Patients without contraindications of bronchoscopy. * Patients have good medical adherence and signed informed consent. Exclusion Criteria: * Peripheral pulmonary lesion is pure ground-glass opacity. * Visible lumen lesions during bronchoscopy * The lesions were adjacent to the central airway (trachea, left and right main bronchus, and right middle bronchus), and the biopsies by the Thin Convex Probe EBUS Scope BF-UC290F were conducted without leaf bronchus entry * The investigators believe that patient has other conditions that are not suitable for the study.