Hypovolemia caused by acute bleeding increased morbi-mortality in emergency and operatin rooms. Precise real-time diagnosis of incipient acute hypovolemia is lacking at the bedside. We hypothesize that the infrared-red signals of pulse oximetry are sensitive to acute changes in patient's volemia. We aimed to test this hypothesis in a cohort of healthy blood donors as a model of simulated acute hypovolemia.
This is a prospective and observational study designed to determine if the changes observed in finger photoplethysmographic waveform can detect incipient hypovolemia. The investigators will studied 60 blood donor volunteers as a model of slight hypovolemia (8-10% of the volemia). Vital signs and photoplethysmography will be recorded in the thumb of the tested hand during a standard blood donation protocol. Recorded data will be analyzed and compared before and after blood donation .
Study Type
OBSERVATIONAL
Enrollment
60
Finger photoplethysmography in tested hand, noninvasive blood pressure and heart rate during blood donation.
Hospital Privado de Comunidad
Mar del Plata, Buenos Aires, Argentina
Analysis of the continuous component (DC) of the photoplethysmography signal.
The DC components of photoplethysmography is measured in arbitrary units (a.u).
Time frame: 15 minutes
Analysis of non-invasive arterial blood pressure (NIBP)
NIBP is recorded in mmHg. This information is analyzed before and after blood donation.
Time frame: 15 minutes
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