Postoperative ileus (POI) after colorectal surgery is frequent and is a burden for national health authority because it increases the morbidity and the length of hospital stay. Some of the stage of the mechanism of POI are known and are now targeted to reduce its occurence but despite these measures, POI still happens in 10-30% of surgeries. The role of the intestinal microbiota in POI is unknown while it could be a new target to reduce its duration or its occurence.
Study Type
OBSERVATIONAL
Enrollment
64
Feces will be collected, at home, by the patient., by using a collection kit. The stools are collected in the 2 last days before surgery. After surgery, the first stool is collected, during the hospitalization, by using the same kit. Stools are conserved in the same condition, before being frozen in our local biologic ressources center.
Angers University Hospital, visceral and endocrine surgery department
Angers, France
Composition of the feces microbiota before surgery
The composition of the microbiota will be assessed by the analysis of the region V3 V4 of the 16S rRNA, amplificateur by high flow sequencing
Time frame: within the 2 last days before surgery
Composition of the feces microbiota after surgery
The composition of the microbiota will be assessed by the analysis of the region
Time frame: up to the first postoperative stools, an average of 3 postoperative days
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